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Cancer Find Up for Year’s Biggest Biomedical Advance in a Different ‘March Madness’
For the third year in a row, a discovery from the University of Virginia School of Medicine has been selected as one of the year’s most significant biomedical discoveries. The finding – identifying the gene responsible for one of the deadliest cancers – is among 64 contenders fighting it out to win the public’s votes in an online bracket tournament.
Voting opens today for “STAT Madness,” which is like the scientific version of the NCAA basketball tournament. The annual competition is sponsored by the STAT health news site to identify the year’s “best biomedical innovation,” and you can vote by clicking here. The first round is open through Sunday.
A type of ultrasound scan can detect cancer tissue left behind after a brain tumor is removed more sensitively than surgeons, and could improve the outcome from operations, a new study suggests.
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IMAGE: Cell membranes contain channels that selectively permit ions to move into or out of the cell. In a recently published paper, researchers from the University of Fukui and Kanazawa University. view more
Credit: University of Fukui
The cell membranes of all organisms contain ion channels that permit ions to pass into or out of the cell, and these channels play extremely important roles in fundamental physiological processes such as heartbeats and the rapid conduction of signals along neurons. An important property of these ion channels is their selective conductivity they selectively permit the passage of particular ions. For example, potassium channels more readily permit the passage of potassium ions than the passage of sodium ions, despite the fact that potassium ions are larger.
Obstructive sleep apnea is when breathing is repeatedly interrupted during sleep. Research has shown people with this sleep disorder have an increased risk of developing cognitive impairment and Alzheimer s disease. Yet, it is treatable. A preliminary study released today, February 28, 2021, has found that obstructive sleep apnea is common in people with cognitive impairment. The study will be presented at the American Academy of Neurology s 73rd Annual Meeting being held virtually April 17 to 22, 2021.
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IMAGE: High-throughput total RNA-seq profile for PLCγ1 and PLCβ subfamily gene expression in the cortex view more
Credit: KBRI
Korea Brain Research Institute (KBRI, President Suh Pann-ghill) announced that the research team led by Dr. Jae-Yeol Joo discovered new cryptic splice variants and SNVs in PLCg1 gene of AD-specific models for the first time using Splice-AI.
This research outcome was published in
PNAS, a world-renowned academic journal. (Title) Prediction of Alzheimer s Disease-Specific phospholipase c gamma-1 SNV by Deep Learning-Based Approach for High-Throughput Screening Alternative splicing variant regulates gene expression and influences diverse phenotypes. Especially, genetic variants arising due to RNA splicing are frequently found in individuals having neurodevelopmental disorders.